Visual Temporal Resolution in Patients with Sickle Cell Anemia
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Abstract
The Nervous System (NS) is affected in patients with Sickle Cell Anemia (SCA). The Visual Temporal Resolution (VTR) is considered as a measure of processing speed and cortical activation. It is used as general indicator of NS functioning, and it can be tested by Critical Frequency Fusion (CFF). The CFF was examined in 84 patients without previous neurologic events and the same amount in healthy subjects. The participants were ranging in age from 8 to 68. The patients’ hemoglobin level was measured at the moment of the neuropsychological assessment. The patients’ CFF was significantly lower than healthy people. Age correlated inversely with CFF, and statistically significant associations between hemoglobin and CFF was not found. We concluded that VTR is diminished en patients with SCA, which suggests that neurodevelopment is affected due to SCA.
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References
Aisenberg, R. B., Rosenthal, A., Wolff, P. H., & Nadas, A. S. (1974). Hypoxemia and Critical Flicker Frequency in Congenital Heart Disease. Am J Dis Child., 128(3), 335-338.
Ballas, S., Kesen, M., Goldberg, M., Lutty, G., Dampier, C., Osunkwo, I. et al. (2012). Beyond the Definitions of the Phenotypic Complications of Sickle Cell Disease: An Update on Management. Scientific World Journal, 2012, 949535.
Bernardi, L., Costa, V. P., & Shiroma, L. O. (2007). Flicker perimetry in healthy subjects: influence of age and gender, learning effect and short-term fluctuation. Arq Bras Oftalmol., 70, 91–99.
Bourque, S., Kuny, S., Reyes, L., Davidge, S., & Sauvé, Y. (2013). Prenatal Hypoxia Is Associated with Long-Term Retinal Dysfunction in Rats. PLoS One, 8(4), 61861.
Colombatti, R., Ermani, M., Rampazzo, P., Manara, R., Montanaro, M., Basso, G. et al. (2015). Cognitive evoked potentials and neural networks are abnormal in children with sickle cell disease and not related to the degree of anaemia, pain and silent infarcts. British Journal of Haematology, 169, 597-600.
Crosby, L. E., Quinn, C. T., & Kalinyak, K. A. (2015). A Biopsychosocial Model for the Management of Patients With Sickle-Cell Disease Transitioning to Adult Medical Care. Advances in Therapy, 32(4), 293-305.
Detaum, M., Armstrong, F. D., McKinstry, R. C., Ware, R. E., Vichinsky, E., & Kirkham, F. J. (2012). Silent cerebral infarcts: a review on a prevalent and progresive cause of neurologic injury in sickle cell disease. Blood, 119, 4587-4596.
Ellemberg D., Lewis, T. L., Liu, C. H., & Maurer, D. (1999). Development of spatial and temporal vision during childhood. Vision Research, 39, 2325-2333.
Healy, K., McNally, L., Ruxton, G. D., Cooper, N., & Jackson, A. L. (2013). Metabolic rate and body size are linked with perception of temporal information. Anim Behav., 86(4), 685-696.
IanIampietro, M., Giovannetti, T., & Tarazi, R. (2014). Hypoxia and inflammation in children with sickle cell disease: implications for hippocampal functioning and episodic memory. Neuropsychol Rev, 24(2), 252-265.
Kato, G. J. (2012). Anemia, age, desaturation and impaired neurocognition in Sickle Cell Anemia. Pediatr Blood Cancer, 59(5), 773-774.
Kot, J., Winklewski, P., Sicko, Z., & Tkachenko, Y. (2015). Effect of oxygen on neuronal excitability measured by critical flicker fusion frequency is dose dependent. Journal of Clinical and Experimental Neuropsychology, 37(3), 276-284.
Nardella, A., Rocchi, L., Conte, A., Bologna, M., Suppa, A., & Berardelli, A. (2014). Inferior Parietal Lobule Encodes Visual Temporal Resolution Processes Contributing to the Critical Flicker Frequency Threshold in Humans. PLoS ONE, 9(6), e98948.
Petukhov, I. V., Rozhentsov, V. V., & Aliev, M. T. (2007). On the accuracy of evaluations of temporal characteristics of visual perception. Bull Exp Biol Med., 144, 267-268.
Schatz, J., Finke, R. L., Kellett, J. M., & Kramer, J. H. (2002). Cognitive functioning in children with sickle cell disease: a meta-analysis. J Pediatr Psychol, 27, 739-748.
Schatz, J. & Roberts, C. W. (2007). Neurobehavioral impact of sickle cell disease in early chilhood. J Int Neuropsychol Soc., 13, 933-943.
Schatz, J., McClellan, C. B., Puffer, E. S., Johnson, K., & Roberts, C.W. (2008). Neurodevelopmental screening in toddlers and early preschoolers with sickle cell disease. J Child Neurol., 23, 44-50.
Seitz, A. R., Nanez, J. E., Holloway, S. R., & Watanabe, T. (2005). Visual experience can substantially alter critical flicker fusion thresholds. Hum Psychopharmaco, 20, 55-60.
Vichinsky, E. P., Neumayr, L. D., Gold, J. I., Weiner, M. W., Rule, R. R., Truran, D. et al. (2010). Neuropsychological dysfunction and neuroimaging abnormalities in neurologically intact adults with sickle cell anemia. JAMA, 303, 1823-1831.
Zou, P., Helton, K. J., Smeltzer, M., Li, C. S., Conklin, H. M., Gajjar, A. et al. (2011) Hemodynamic responses to visual stimulation in children with Sickle Cell Anemia. Brain Imaging Behavior, 5(4), 295-306.